Perovial®
Medical device
Perovial® is the first intra-penile Hyaluronic acid (HA)-based option in the UK for the management of Peyronie’s disease in its acute phase1.

Highlights
High level of novelty
Classified as a high level of novelty device1
Improvement
Can improve penile curvature, plaque size, and erectile function3,4,5,6
Improves outcome
Improves outcome in terms of penile pain reduction and patients’ satisfaction4,5
Tolerability
Well-tolerated in clinical studies3,4,5
Protocol
Weekly for 10-12 weeks according to the doctor’s professional clinical assessment2
Clinical evidence
Clinical studies show:
Regression in plaque size5,6
Perovial® leads to a measurable decrease in penile curvature3,4,5,6
Perovial® improves erectile function4,5
Perovial® showed significant improvement in penile pain compared to verapamil and baseline and patient satisfaction4,5,6
Perovial® was well-tolerated in clinical studies3,4,5
Additional resources
If your patient gets any side-effects, please report them. This includes any possible side effects not listed in the package leaflet. You can also report side-effects directly via the Yellow Card Scheme at yellowcard.mhra.gov.uk.
To report a side effect or product complaint to IBSA Pharma please contact IBSA Pharma Ltd on 01923 233466 and medicalinformation.uk@ibsagroup.com.

References
- 1 / European Commission. Expert decision and opinion in the context of the Clinical Evaluation Consultation Procedure (CECP).
- 2 / PEROVIAL®. Instructions for Use.
- 3 / Favilla V, et al. Andrology. 2017;5(4):771-5.
- 4 / Iaconisi GN, et al. Int J Mol Sci. 2023;24(12):10296.
- 5 / Cocci A, et al. World J Mens Health. 2021;39(2):352-7.
- 6 / Zucchi A, et al. Sex Med. 2016;4(2):e83-8.
- 7 / Cai T, et al. World J Mens Health. 2021;39(3):526-32.


